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Señalización celular y daño génico en cáncer y neurodegeneración

The VRK1 signaling pathway in the context of the proliferation phenotype in head and neck squamous cell carcinoma
Santos CR, Rodríguez-Pinilla M, Vega FM, Rodríguez-Peralto JL, Blanco S, Sevilla A, Valbuena A, van Wijnen AJ, Li F, Sánchez-Céspedes M, Lazo PA.
Molecular Cancer Research 4: 177-185. FI: 5.310 (Q1)
PubMed
Subcellular localization of vaccinia-related kinase 2 (VRK2) isoforms determines their different effect on p53 stability in tumour cell lines
Blanco S, Klimcakova L, Vega FM, Lazo PA.
The FEBS Journal 273: 2487-2504. FI: 3.400 (Q2)
PubMed
p53 downregulates its activating vaccinia-related kinase 1 (VRK1) forming a new autoregulatory loop
Valbuena A, Vega FM, Blanco S, Lazo PA.
Molecular and Cell Biology 26:4782-4793. FI: 7.093 (Q1)
PubMed
The vaccinia virus B1R kinase interacts with JIP1 and modulates c-Jun dependent signaling
Santos CR, Blanco S, Sevilla A, Lazo PA.
Journal of Virology 80:7667-7675. FI: 5.341 (Q1)
PubMed
Identification of a dominant epitope in human vaccinia-related kinase 1 (VRK1) and detection of different intracellular subpopulations
Valbuena A, López-Sánchez I, Vega FM, Sevilla A, Sanz-García M, Blanco S, Lazo PA.
Archives of Biochemistry and Biophysics 465:219-226. FI: 2.969 (Q2)
PubMed
Disruption of the VRK1-p53 autoregulatory loop in human lung carcinomas
Valbuena A, Suárez-Gauthier A, López-Ríos F, López-Encuentra A, Blanco S, Fernández PL, Sánchez-Céspedes M, Lazo PA.
Lung Cancer 58: 303-309. FI: 3.554 (Q2)
PubMed
Functional implications of tetraspanin proteins in cancer biology
Lazo PA.
Cancer Science 98:1666-1677. FI: 3.869 (Q2)
PubMed
Vaccinia-related kinase 2 modulates the stress response to hypoxia mediated by TAK1
Blanco S, Santos CR, Lazo PA.
Molecular and Cellular Biology 27:7273-7283. FI: 7.093 (Q1)
PubMed
Modulation of interleukin1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein
Blanco S, Sanz-García M, Santos CR, Lazo PA.
PLoS ONE 3: e1660. FI: 4.610 (Q1)
PubMed
Human VRK1 is an early response gene and its loss causes a block in cell cycle progression
Valbuena A, López-Sánchez I, Lazo PA.
PLoS ONE 3: e1642. FI: 4.610 (Q1)
PubMed

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