Conditional cysteine restriction in mice causes substantial weight loss, exceeding that seen with essential amino acid restriction, by activating the integrated stress and oxidative stress responses, and by unexpectedly depleting coenzyme A, leading to metabolic inefficiency.

A planet in a retrograde orbit around a star with a close-in white dwarf companion reveals the role of binary stellar evolution in the formation and evolution of planets.

The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing through cellular differentiation at scale.

CRISPR-TO, a system for programmable control of spatial localization of cellular RNAs, is presented and enables functional investigation of endogenous RNA localization in diverse living cells.

Gas distribution and motion patterns driven by a galactic bar of the J0107a dusty star-forming galaxy have analogues in local bars, indicating that similar processes of active star formation were already operating 11.1 billion years ago.